What is GHK-CU?

GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) is a naturally occurring peptide made up of three amino acids attached to a copper ion. Your body naturally produces GHK-Cu, and it is found in your blood, saliva, and urine. It plays an important role in the body’s natural repair process by supporting collagen production, tissue healing, and healthy skin. Scientists first discovered GHK-Cu in 1973 while studying human blood plasma. Since then, it has become one of the most researched peptides in dermatology and wound healing. Researchers have spent more than 50 years studying its potential role in skin repair, collagen production, hair growth, and tissue regeneration. One reason GHK-Cu has attracted so much interest is that natural levels decline as we age. As these levels decrease, the body’s ability to repair and maintain healthy tissues may also change. Researchers are studying whether replacing GHK-Cu can help support the body’s normal healing and repair processes. Because GHK-Cu contains copper, it should be used under the supervision of a qualified healthcare provider. Copper is an essential mineral that the body needs, but excessive amounts can be harmful. Your provider may recommend periodic blood tests to help ensure your copper levels remain in a healthy range. Topical GHK-Cu is currently available through licensed compounding pharmacies. The injectable form is scheduled for review by the FDA’s Compounding Advisory Committee in February 2027. During that meeting, the committee will review the available scientific evidence and make recommendations regarding whether injectable GHK-Cu is appropriate for compounding by licensed pharmacies.